In this diagram you see how in healthy tissue a fine mesh or blood and lymph channels supplies the adipose tissue with necessary nutrition and oxygen for the removal of toxic elements.

 In unhealthy tissue, the microcirculation of both blood and lymph has been disrupted by constricted and loss of dermal capillary networks. Engorged fat cells causing decreased circulation in the unhealthy tissue contributes to an inflammatory response.  This causes structural changes in subcutaneous fat tissue and the surrounding matrix of collagen fibers reflecting the expansion of adipose tissue into the dermis and the stiffening of collagen fibers that draw in anchor points causing dimpling in the dermis and epidermis.